Venture/VC

Rod Cotton is an entrepreneurial board member, venture partner, and advisor with over 40 years of executive experience in public, private, and start-up biotech and tech-driven healthcare companies.

He currently serves as an independent director and audit and compensation member at Castle Biosciences (Nasdaq: CSTL) and holds independent directorships at Eisai Pharmaceuticals (U.S), Moleculera Biosciences, Orchard Software, and General Genomics. Rod is also a venture partner at 2Flo Ventures. Previously, he spent over two decades at Roche Diagnostics, culminating in roles like SVP, Head of Strategy & Transformation, and Chief of Staff to the CEO.

Recognized by Savoy Magazine, BlackDoctor.org, and BoardProspects, Rod has received accolades like Most Influential Corporate Directors and Top Blacks in Healthcare.

He holds an MBA from California State University, Dominguez Hills, an MS in Strategic Management from the University of Southern California, and a BA in Biological Sciences and Technology from the University of California, Santa Barbara.

About Rod Cotton

Venture Capital (Portfolio Companies)

2Flo Ventures

2Flo Ventures is a Chicago-based startup studio and venture capital firm, founded in 2021, that advances health equity by investing over $85 million in early-stage therapeutics, medical devices, diagnostics, and digital health, and recently launched a $50M second fund to continue accelerating equitable innovation.

Vivacelle Bio is a late-stage biopharmaceutical company focused on developing life-saving treatments for shock and trauma, with its lead candidate VBI-S effectively restoring blood pressure and improving organ function using patented phospholipid nanoparticle technology.

Vivacelle Bio

Temprian Therapeutics

Temprian Therapeutics, a Chicago-based biotech spin-off from Northwestern University, is developing a gene therapy for vitiligo that uses a genetically modified DNA plasmid to restore pigmentation by modulating the immune response, with potential applications for other autoimmune disorders.

Rod’s Story

Rod Cotton plays a vital role in the venture capital ecosystem as a seasoned operator, trusted board advisor, and strategic thought partner to founders navigating the high-stakes early stages of biotech and health tech growth. As a venture partner at 2Flo Ventures — a healthcare and health equity accelerator — Rod works directly with portfolio companies to shape go-to-market strategies, streamline operations, and ensure clinical and commercial alignment. His contributions don’t end at oversight; he’s in the trenches, helping mission-driven startups define their impact while remaining fundable, scalable, and focused.

Rod's value to founders stems from his rare ability to translate complex science into real-world value, earned through decades of executive leadership in diagnostics, pharmaceuticals, and strategic transformation. Having led multi-billion-dollar business units, managed large-scale P&Ls and mergers and acquisitions, Rod understands both the speed and discipline required to build a company that lasts. Startups seek his mentorship not only for his business rigor but for his authenticity — he meets founders with clarity, candor, and a collaborative spirit.

Through his advisory and board roles with early-stage companies like General Genomics, Moleculera Biosciences and 2Flo Ventures, Rod is advancing a new generation of health innovation rooted in equity, precision and access. He believes venture capital is not just about accelerating capital returns, but about accelerating human impact — and his role is to make sure both happen with integrity. Whether in the lab, the boardroom, or the pitch deck, Rod brings the vision and experience to move companies forward with purpose.

Deep Expertise, Strategic Vision

“Rod’s deep expertise in therapeutics, diagnostics and devices aligns with our mission to advance health equity and tackle unmet medical needs. His strategic vision will strengthen our ability to support innovative companies and generate meaningful impact.

We’re excited to embark on this journey together to transform healthcare solutions for a better future.”

— 2Flo Ventures

“Congratulations, Rod! Joining 2Flo Ventures, with its bold mission to advance equity and innovation in healthcare, is such an inspiring move.

— Merritt McKenzie

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